![]() ![]() It initially occurred mainly in India and Pakistan, and specifically in New Delhi, where the climate encourages its persistence year round. The gene for this is widespread in bacteria found in India and Pakistan, especially in hospitals. The people who discovered the NDM-1 protein named it after New Delhi, the Indian capital. Share on Pinterest Scientists expect that secondary NDM-1 viruses will spread without a person having come into contact with India. Research is on-going into possible solutions to NDM-1. EvenĬarbepenems are ineffective in cases of NDM-1.Ī bacterium with a plasmid containing the NDM-1 protein product has the potential to be resistant to many current antibiotics, as well as newer antibiotics that could become available in the near future. ![]() Carbapenemase renders many preferred types of antibiotic ineffective, including carbapenems.Ĭarbapenem antibiotics are extremely powerful drugs that can counter the activity of highly resistant bacteria for which other antibiotics have not been effective. The NDM-1 gene causes bacteria to produce an enzyme called a carbapenemase. In this case, no treatment options would be available that are safe for a woman during pregnancy. The WHO suggest that a woman who is pregnant, for example, could develop a kidney infection that transfers into the bloodstream with a strain containing NDM-1. If NDM-1 crosses over into other bacteria, secondary diseases will emerge, causing a health crisis as they spread around the world. NDM-1 raises fears that diseases in the future will not respond to antibiotics. The World Health Organization (WHO) is concerned that NDM-1 could see in “the doomsday scenario of a world without antibiotics.”īefore the discovery of antibiotics in 1928, many people died because of infections that are now avoidable. MRSA are a Gram-positive bacteria, while the bacteria that carry NDM-1 are Gram-negative, a different classification of bacteria. The NDM-1 protein is different from the protein product that characterizes methicillin-resistant Staphylococcus aureus ( MRSA), another superbug. The Centers for Disease Control and Prevention (CDC) have classified NDM-1 and another similar protein called KPC as emerging issues in the field of infectious diseases.Ī bacterium carrying the NDM-1 gene is considered a very powerful superbug. The NDM-1 gene allows the bacterium to produce an enzyme that neutralizes the activity of these antibiotics. Healthcare professionals use them as a last resort for many bacterial infections, such as those that E. ![]() In this way, it can lead to a range of conditions, such as a urinary tract, bloodstream, or wound infections and pneumonia.Ĭarbapenems are among the most powerful antibiotics. The gene makes bacteria resistant to antibiotics. The NDM-1 protein product itself does not cause disease, but it has the potential to change the characteristics of bacteria. Share on Pinterest An NDM-1 superbug is resistant to almost all antibiotics. ![]()
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